DNA Methylation Changes Separate Allergic Patients from Healthy Controls and May Reflect Altered CD4+ T-Cell Population Structure

DNA Methylation Changes Separate Allergic Patients from Healthy Controls and May Reflect Altered CD4+ T-Cell Population Structure

Altered DNA methylation patterns in CD4+ T-cells indicate the importance of epigenetic mechanisms in inflammatory diseases. However, the identification of these alterations is complicated by the heterogeneity of most inflammatory diseases. Seasonal allergic rhinitis (SAR) is an optimal disease model...

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Bibliographic Details
Main Authors: Nestor, Colm E., Barrenäs, Fredrik, Wang, Hui, Lentini, Antonio, Zhang, Huan, Bruhn, Sören, Jörnsten, Rebecka, Langston, Michael A., Rogers, Gary, Gustafsson, Mika, Benson, Mikael
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879208/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879208/

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