Diffuse neurofibroma - an uncommon cause of alopecia*

Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. His...

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Main Authors:	Macias, Vasco Coelho, Rafael, Margarida, Fernandes, Cândida, Rosa, Joaninha Costa
Format:	Online
Language:	English
Published:	Sociedade Brasileira de Dermatologia 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876007/

id	pubmed-3876007
recordtype	oai_dc
spelling	pubmed-38760072014-01-08 Diffuse neurofibroma - an uncommon cause of alopecia* Macias, Vasco Coelho Rafael, Margarida Fernandes, Cândida Rosa, Joaninha Costa Case Report Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofibromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques. Sociedade Brasileira de Dermatologia 2013 /pmc/articles/PMC3876007/ /pubmed/24346909 http://dx.doi.org/10.1590/abd1806-4841.20132170 Text en ©2013 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Macias, Vasco Coelho Rafael, Margarida Fernandes, Cândida Rosa, Joaninha Costa
spellingShingle	Macias, Vasco Coelho Rafael, Margarida Fernandes, Cândida Rosa, Joaninha Costa Diffuse neurofibroma - an uncommon cause of alopecia*
author_facet	Macias, Vasco Coelho Rafael, Margarida Fernandes, Cândida Rosa, Joaninha Costa
author_sort	Macias, Vasco Coelho
title	Diffuse neurofibroma - an uncommon cause of alopecia*
title_short	Diffuse neurofibroma - an uncommon cause of alopecia*
title_full	Diffuse neurofibroma - an uncommon cause of alopecia*
title_fullStr	Diffuse neurofibroma - an uncommon cause of alopecia*
title_full_unstemmed	Diffuse neurofibroma - an uncommon cause of alopecia*
title_sort	diffuse neurofibroma - an uncommon cause of alopecia*
description	Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofibromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques.
publisher	Sociedade Brasileira de Dermatologia
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876007/
_version_	1612042545755324416

Diffuse neurofibroma - an uncommon cause of alopecia*

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