Allogeneic hematopoietic stem cell transplantation in mycosis fungoides*
Mycosis Fungoides is typically an indolent disease in early stages. However, approximately 30% of patients have advanced staged disease at presentation and 20% will develop it at some time. These patients have a poorer prognosis with a median survival of 2-4 years. The only curative option for mycos...
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| Language: | English |
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Sociedade Brasileira de Dermatologia
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875963/ |
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pubmed-3875963 |
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pubmed-38759632014-01-08 Allogeneic hematopoietic stem cell transplantation in mycosis fungoides* Atalla, Angelo Hallack Neto, Abrahão Elias Siqueira, Denise Bittencourt Toledo, Gabriela Cumani Case Report Mycosis Fungoides is typically an indolent disease in early stages. However, approximately 30% of patients have advanced staged disease at presentation and 20% will develop it at some time. These patients have a poorer prognosis with a median survival of 2-4 years. The only curative option for mycosis fungoides may be hematopoietic allogeneic stem cell transplantation. We report the case of a patient with mycosis fungoides in an advanced stage (IIB), refractory to treatment options. She underwent allogeneic hematopoietic stem-cell transplantation (allo-HSCT). The patient remains in complete remission nineteen months after allo-HSCT. Allogeneic transplantation can alter the natural history of mycosis fungoides and should be considered in patients who have refractory disease or short-lived responses with standard therapies. Sociedade Brasileira de Dermatologia 2013 /pmc/articles/PMC3875963/ /pubmed/24346924 http://dx.doi.org/10.1590/abd1806-4841.20132365 Text en ©2013 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Atalla, Angelo Hallack Neto, Abrahão Elias Siqueira, Denise Bittencourt Toledo, Gabriela Cumani |
| spellingShingle |
Atalla, Angelo Hallack Neto, Abrahão Elias Siqueira, Denise Bittencourt Toledo, Gabriela Cumani Allogeneic hematopoietic stem cell transplantation in mycosis fungoides* |
| author_facet |
Atalla, Angelo Hallack Neto, Abrahão Elias Siqueira, Denise Bittencourt Toledo, Gabriela Cumani |
| author_sort |
Atalla, Angelo |
| title |
Allogeneic hematopoietic stem cell transplantation in mycosis
fungoides*
|
| title_short |
Allogeneic hematopoietic stem cell transplantation in mycosis
fungoides*
|
| title_full |
Allogeneic hematopoietic stem cell transplantation in mycosis
fungoides*
|
| title_fullStr |
Allogeneic hematopoietic stem cell transplantation in mycosis
fungoides*
|
| title_full_unstemmed |
Allogeneic hematopoietic stem cell transplantation in mycosis
fungoides*
|
| title_sort |
allogeneic hematopoietic stem cell transplantation in mycosis
fungoides* |
| description |
Mycosis Fungoides is typically an indolent disease in early stages. However,
approximately 30% of patients have advanced staged disease at presentation and 20%
will develop it at some time. These patients have a poorer prognosis with a median
survival of 2-4 years. The only curative option for mycosis fungoides may be
hematopoietic allogeneic stem cell transplantation. We report the case of a patient
with mycosis fungoides in an advanced stage (IIB), refractory to treatment options.
She underwent allogeneic hematopoietic stem-cell transplantation (allo-HSCT). The
patient remains in complete remission nineteen months after allo-HSCT. Allogeneic
transplantation can alter the natural history of mycosis fungoides and should be
considered in patients who have refractory disease or short-lived responses with
standard therapies. |
| publisher |
Sociedade Brasileira de Dermatologia |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875963/ |
| _version_ |
1612042520180555776 |