Corpus callosal microstructure influences intermanual transfer in chimpanzees
Learning a new motor skill with one hand typically results in performance improvements in the alternate hand. The neural substrates involved with this skill acquisition are poorly understood. We combined behavioral testing and non-invasive brain imaging to study how the organization of the corpus ca...
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| Format: | Online |
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Frontiers Media S.A.
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875866/ |
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pubmed-38758662014-01-14 Corpus callosal microstructure influences intermanual transfer in chimpanzees Phillips, Kimberley A. Schaeffer, Jennifer A. Hopkins, William D. Neuroscience Learning a new motor skill with one hand typically results in performance improvements in the alternate hand. The neural substrates involved with this skill acquisition are poorly understood. We combined behavioral testing and non-invasive brain imaging to study how the organization of the corpus callosum was related to intermanual transfer performance in chimpanzees. Fifty-three chimpanzees were tested for intermanual transfer of learning using a bent-wire task. Magnetic resonance and diffusion tensor images were collected from 39 of these subjects. The dominant hand showed greater performance benefits than the nondominant hand. Further, performance was associated with structural integrity of the motor and sensory regions of the CC. Subjects with better intermanual transfer of learning had lower fractional anisotropy values. The results are consistent with the callosal access model of motor programming. Frontiers Media S.A. 2013-12-31 /pmc/articles/PMC3875866/ /pubmed/24427118 http://dx.doi.org/10.3389/fnsys.2013.00125 Text en Copyright © 2013 Phillips, Schaeffer and Hopkins. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Phillips, Kimberley A. Schaeffer, Jennifer A. Hopkins, William D. |
| spellingShingle |
Phillips, Kimberley A. Schaeffer, Jennifer A. Hopkins, William D. Corpus callosal microstructure influences intermanual transfer in chimpanzees |
| author_facet |
Phillips, Kimberley A. Schaeffer, Jennifer A. Hopkins, William D. |
| author_sort |
Phillips, Kimberley A. |
| title |
Corpus callosal microstructure influences intermanual transfer in chimpanzees |
| title_short |
Corpus callosal microstructure influences intermanual transfer in chimpanzees |
| title_full |
Corpus callosal microstructure influences intermanual transfer in chimpanzees |
| title_fullStr |
Corpus callosal microstructure influences intermanual transfer in chimpanzees |
| title_full_unstemmed |
Corpus callosal microstructure influences intermanual transfer in chimpanzees |
| title_sort |
corpus callosal microstructure influences intermanual transfer in chimpanzees |
| description |
Learning a new motor skill with one hand typically results in performance improvements in the alternate hand. The neural substrates involved with this skill acquisition are poorly understood. We combined behavioral testing and non-invasive brain imaging to study how the organization of the corpus callosum was related to intermanual transfer performance in chimpanzees. Fifty-three chimpanzees were tested for intermanual transfer of learning using a bent-wire task. Magnetic resonance and diffusion tensor images were collected from 39 of these subjects. The dominant hand showed greater performance benefits than the nondominant hand. Further, performance was associated with structural integrity of the motor and sensory regions of the CC. Subjects with better intermanual transfer of learning had lower fractional anisotropy values. The results are consistent with the callosal access model of motor programming. |
| publisher |
Frontiers Media S.A. |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875866/ |
| _version_ |
1612042465884241920 |