Interleukin-4 and interleukin-13 cause barrier dysfunction in human airway epithelial cells

Emerging evidence indicates that airway epithelial barrier function is compromised in asthma, a disease characterized by Th2-skewed immune response against inhaled allergens, but the mechanisms involved are not well understood. The purpose of this study was to investigate the effects of Th2-type cyt...

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Bibliographic Details
Main Authors: Saatian, Bahman, Rezaee, Fariba, Desando, Samantha, Emo, Jason, Chapman, Tim, Knowlden, Sara, Georas, Steve N.
Format: Online
Language:English
Published: Landes Bioscience 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875607/