Frequent truncating mutations of STAG2 in bladder cancer

Frequent truncating mutations of STAG2 in bladder cancer

Here we report the discovery of truncating mutations of the gene encoding the cohesin subunit STAG2, which regulates sister chromatid cohesion and segregation, in 36% of papillary non-invasive urothelial carcinomas and 16% of invasive urothelial carcinomas of the bladder. Our studies suggest that ST...

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Bibliographic Details
Main Authors: Solomon, David A., Kim, Jung-Sik, Bondaruk, Jolanta, Shariat, Shahrokh F., Wang, Zeng-Feng, Elkahloun, Abdel G., Ozawa, Tomoko, Gerard, Julia, Zhuang, DaZhong, Zhang, Shizhen, Navai, Neema, Siefker-Radtker, Arleen, Phillips, Joanna J., Robinson, Brian D., Rubin, Mark A., Volkmer, Björn, Hautmann, Richard, Küfer, Rainer, Hogendoorn, Pancras C. W., Netto, George, Theodorescu, Dan, James, C. David, Czerniak, Bogdan, Miettinen, Markku, Waldman, Todd
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875130/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875130/

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