Expression of VEGF and Flk-1 and Flt-1 Receptors during Blood-Brain Barrier (BBB) Impairment Following Phoneutria nigriventer Spider Venom Exposure

Apart from its angiogenic and vascular permeation activity, the vascular endothelial growth factor (VEGF) has been also reported as a potent neuronal protector. Newborn rats with low VEGF levels develop neuron degeneration, while high levels induce protective mechanisms in several neuropathological...

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Bibliographic Details
Main Authors: Mendonça, Monique C. P., Soares, Edilene S., Stávale, Leila M., Rapôso, Catarina, Coope, Andressa, Kalapothakis, Evanguedes, da Cruz-Höfling, Maria Alice
Format: Online
Language:English
Published: MDPI 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873701/