cis-Acting Elements and trans-Acting Factors in the Transcriptional Regulation of Raf Kinase Inhibitory Protein Expression

The Raf kinase inhibitory protein (RKIP) is down-regulated in multiple types of human cancers. Decreased RKIP transcription activity may be one of the major mechanisms responsible for the downregulation of RKIP expression in human diseases. To test this hypothesis, we need to gain basic knowledge of...

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Bibliographic Details
Main Authors: Zhang, Boyan, Wang, Ou, Qin, Jingchao, Liu, Shuaishuai, Sun, Sheng, Liu, Huitu, Kuang, Jian, Jiang, Guohua, Zhang, Wei
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873293/