Targeting mitochondrial dysfunction in lung diseases: emphasis on mitophagy
During mild stressful conditions, cells activate a multitude of mechanisms in an attempt to repair or re-establish homeostasis. One such mechanism is autophagic degradation of mitochondria or mitophagy to dispose damaged mitochondria. However, if stress persists beyond recovery then dysfunctional mi...
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2013
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872744/ |