JAK/STAT Signalling in Huntington’s Disease Immune Cells

Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by a CAG repeat expansion in the huntingtin (HTT) gene. Both central and peripheral innate immune activation have been described as features of the disease. Isolated human HD monocytes have been shown to produce more cytokin...

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Bibliographic Details
Main Authors: Träger, Ulrike, Magnusson, Anna, Lahiri Swales, Nayana, Wild, Edward, North, Janet, Lowdell, Mark, Björkqvist, Maria
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871417/