Study of Mutations in the DNA gyrase gyrA Gene of Escherichia coli
Quinolones are a large and widely consumed class of synthetic drugs. Expanded-spectrum quinolones, like ciprofloxacin are highly effective against Gram-negative bacteria, especially Escherichia coli. In E. coli the major target for quinolones is DNA gyrase. This enzyme is composed of two subunits, G...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Shaheed Beheshti University of Medical Sciences
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869551/ |