New developments in gold-catalyzed manipulation of inactivated alkenes
Over the recent years, the nucleophilic manipulation of inactivated carbon–carbon double bonds has gained remarkable credit in the chemical community. As a matter of fact, despite lower reactivity with respect to alkynyl and allenyl counterparts, chemical functionalization of isolated alkenes, via c...
| Main Authors: | , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Beilstein-Institut
2013
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869288/ |
| id |
pubmed-3869288 |
|---|---|
| recordtype |
oai_dc |
| spelling |
pubmed-38692882013-12-23 New developments in gold-catalyzed manipulation of inactivated alkenes Chiarucci, Michel Bandini, Marco Review Over the recent years, the nucleophilic manipulation of inactivated carbon–carbon double bonds has gained remarkable credit in the chemical community. As a matter of fact, despite lower reactivity with respect to alkynyl and allenyl counterparts, chemical functionalization of isolated alkenes, via carbon- as well as hetero atom-based nucleophiles, would provide direct access to theoretically unlimited added value of molecular motifs. In this context, homogenous [Au(I)] and [Au(III)] catalysis continues to inspire developments within organic synthesis, providing reliable responses to this interrogative, by combining crucial aspects such as chemical selectivity/efficiency with mild reaction parameters. This review intends to summarize the recent progresses in the field, with particular emphasis on mechanistic details. Beilstein-Institut 2013-11-21 /pmc/articles/PMC3869288/ /pubmed/24367423 http://dx.doi.org/10.3762/bjoc.9.294 Text en Copyright © 2013, Chiarucci and Bandini; licensee Beilstein-Institut. http://www.beilstein-journals.org/bjoc This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (http://www.beilstein-journals.org/bjoc) |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Chiarucci, Michel Bandini, Marco |
| spellingShingle |
Chiarucci, Michel Bandini, Marco New developments in gold-catalyzed manipulation of inactivated alkenes |
| author_facet |
Chiarucci, Michel Bandini, Marco |
| author_sort |
Chiarucci, Michel |
| title |
New developments in gold-catalyzed manipulation of inactivated alkenes |
| title_short |
New developments in gold-catalyzed manipulation of inactivated alkenes |
| title_full |
New developments in gold-catalyzed manipulation of inactivated alkenes |
| title_fullStr |
New developments in gold-catalyzed manipulation of inactivated alkenes |
| title_full_unstemmed |
New developments in gold-catalyzed manipulation of inactivated alkenes |
| title_sort |
new developments in gold-catalyzed manipulation of inactivated alkenes |
| description |
Over the recent years, the nucleophilic manipulation of inactivated carbon–carbon double bonds has gained remarkable credit in the chemical community. As a matter of fact, despite lower reactivity with respect to alkynyl and allenyl counterparts, chemical functionalization of isolated alkenes, via carbon- as well as hetero atom-based nucleophiles, would provide direct access to theoretically unlimited added value of molecular motifs. In this context, homogenous [Au(I)] and [Au(III)] catalysis continues to inspire developments within organic synthesis, providing reliable responses to this interrogative, by combining crucial aspects such as chemical selectivity/efficiency with mild reaction parameters. This review intends to summarize the recent progresses in the field, with particular emphasis on mechanistic details. |
| publisher |
Beilstein-Institut |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869288/ |
| _version_ |
1612040272043048960 |