Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation

Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation

Induction of antigen-specific CD8+ T cells offers the prospect of immunization against many infectious diseases, but no subunit vaccine has induced CD8+ T cells that correlate with efficacy in humans. Here we demonstrate that a replication-deficient chimpanzee adenovirus vector followed by a modifie...

Full description

Bibliographic Details
Main Authors: Ewer, Katie J., O’Hara, Geraldine A., Duncan, Christopher J. A., Collins, Katharine A., Sheehy, Susanne H., Reyes-Sandoval, Arturo, Goodman, Anna L., Edwards, Nick J., Elias, Sean C., Halstead, Fenella D., Longley, Rhea J., Rowland, Rosalind, Poulton, Ian D., Draper, Simon J., Blagborough, Andrew M., Berrie, Eleanor, Moyle, Sarah, Williams, Nicola, Siani, Loredana, Folgori, Antonella, Colloca, Stefano, Sinden, Robert E., Lawrie, Alison M., Cortese, Riccardo, Gilbert, Sarah C., Nicosia, Alfredo, Hill, Adrian V. S.
Format: Online
Language:English
Published: Nature Pub. Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868203/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868203/

Similar Items