Ribonuclease III mechanisms of double-stranded RNA cleavage

Double-stranded(ds) RNA has diverse roles in gene expression and regulation, host defense, and genome surveillance in bacterial and eukaryotic cells. A central aspect of dsRNA function is its selective recognition and cleavage by members of the ribonuclease III (RNase III) family of divalent-metal-i...

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Bibliographic Details
Main Author: Nicholson, Allen W
Format: Online
Language:English
Published: John Wiley & Sons, Inc. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867540/