Regulation of claudins in blood-tissue barriers under physiological and pathological states

Claudins are pivotal building blocks of tight junctions that form the paracellular barrier in epithelia and endothelia. In mammals, claudins are a 27-gene family that encodes tetraspan membrane proteins, playing a crucial role in the formation and integrity of tight junctions and regulate the barrie...

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Bibliographic Details
Main Authors: Gonçalves, Andreia, Ambrósio, António Francisco, Fernandes, Rosa
Format: Online
Language:English
Published: Landes Bioscience 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867514/