Identification of Candidate Driver Genes in Common Focal Chromosomal Aberrations of Microsatellite Stable Colorectal Cancer

Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. Chromosomal instability (CIN) is a major driving force of microsatellite stable (MSS) sporadic CRC. CIN tumours are characterised by a large number of somatic chromosomal copy number aberrations (SCNA) that frequently affect onco...

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Bibliographic Details
Main Authors: Burghel, George J., Lin, Wei-Yu, Whitehouse, Helen, Brock, Ian, Hammond, David, Bury, Jonathan, Stephenson, Yvonne, George, Rina, Cox, Angela
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867468/