Identification and biochemical analysis of a novel APOB mutation that causes autosomal dominant hypercholesterolemia

Identification and biochemical analysis of a novel APOB mutation that causes autosomal dominant hypercholesterolemia

Patients with autosomal dominant hypercholesterolemia (ADH) have a high risk of developing cardiovascular disease that can be effectively treated using statin drugs. Molecular diagnosis and family cascade screening is recommended for early identification of individuals at risk, but up to 40% of fami...

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Bibliographic Details
Main Authors: Thomas, Ellen R A, Atanur, Santosh S, Norsworthy, Penny J, Encheva, Vesela, Snijders, Ambrosius P, Game, Laurence, Vandrovcova, Jana, Siddiq, Afshan, Seed, Mary, Soutar, Anne K, Aitman, Timothy J
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865582/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865582/

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