Hypothalamic GPR40 Signaling Activated by Free Long Chain Fatty Acids Suppresses CFA-Induced Inflammatory Chronic Pain

GPR40 has been reported to be activated by long-chain fatty acids, such as docosahexaenoic acid (DHA). However, reports studying functional role of GPR40 in the brain are lacking. The present study focused on the relationship between pain regulation and GPR40, investigating the functional roles of h...

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Bibliographic Details
Main Authors: Nakamoto, Kazuo, Nishinaka, Takashi, Sato, Naoya, Mankura, Mitsumasa, Koyama, Yutaka, Kasuya, Fumiyo, Tokuyama, Shogo
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865354/