Structural mechanism of ligand activation in human GABAB receptor
Human GABAB receptor is a G-protein coupled receptor central to inhibitory neurotransmission in the brain. It functions as an obligatory heterodimer of GBR1 and GBR2 subunits. Here we present the first crystal structures of a heterodimeric complex between the extracellular domains of GBR1 and GBR2 i...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865065/ |