Enterohemorrhagic Escherichia coli Hemolysin Employs Outer Membrane Vesicles to Target Mitochondria and Cause Endothelial and Epithelial Apoptosis

Enterohemorrhagic Escherichia coli (EHEC) strains cause diarrhea and hemolytic uremic syndrome resulting from toxin-mediated microvascular endothelial injury. EHEC hemolysin (EHEC-Hly), a member of the RTX (repeats-in-toxin) family, is an EHEC virulence factor of increasingly recognized importance....

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Bibliographic Details
Main Authors: Bielaszewska, Martina, Rüter, Christian, Kunsmann, Lisa, Greune, Lilo, Bauwens, Andreas, Zhang, Wenlan, Kuczius, Thorsten, Kim, Kwang Sik, Mellmann, Alexander, Schmidt, M. Alexander, Karch, Helge
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861543/