Functional Characterization of ECP-Heparin Interaction: A Novel Molecular Model

Human eosinophil cationic protein (ECP) and eosinophil derived neurotoxin (EDN) are two ribonuclease A (RNaseA) family members secreted by activated eosinophils. They share conserved catalytic triad and similar three dimensional structures. ECP and EDN are heparin binding proteins with diverse biolo...

Full description

Bibliographic Details
Main Authors: Hung, Ta-Jen, Tomiya, Noboru, Chang, Tse-Hao, Cheng, Wen-Chi, Kuo, Ping-Hsueh, Ng, Sim-Kun, Lien, Pei-Chun, Lee, Yuan-Chuan, Chang, Margaret Dah-Tsyr
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859622/