Hepatic Crown-Like Structure: A Unique Histological Feature in Non-Alcoholic Steatohepatitis in Mice and Humans

Although macrophages are thought to be crucial for the pathogenesis of chronic inflammatory diseases, how they are involved in disease progression from simple steatosis to non-alcoholic steatohepatitis (NASH) is poorly understood. Here we report the unique histological structure termed “hepatic crow...

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Bibliographic Details
Main Authors: Itoh, Michiko, Kato, Hideaki, Suganami, Takayoshi, Konuma, Kuniha, Marumoto, Yoshio, Terai, Shuji, Sakugawa, Hiroshi, Kanai, Sayaka, Hamaguchi, Miho, Fukaishi, Takahiro, Aoe, Seiichiro, Akiyoshi, Kazunari, Komohara, Yoshihiro, Takeya, Motohiro, Sakaida, Isao, Ogawa, Yoshihiro
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859576/