Autofluorescence endoscopy for the gastrointestinal tract
This review focuses on our basic study results and clinical experience of fluorescence endoscopy for the gastrointestinal (GI) tract. Collagen, which fluoresces in the green wavelength range, is one of the major sources of tissue autofluorescence (AF) and AF imaging systems are now available. With t...
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| Format: | Online |
| Language: | English |
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The Japan Academy
2007
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859293/ |
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pubmed-3859293 |
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pubmed-38592932013-12-23 Autofluorescence endoscopy for the gastrointestinal tract Tajiri, Hisao Review This review focuses on our basic study results and clinical experience of fluorescence endoscopy for the gastrointestinal (GI) tract. Collagen, which fluoresces in the green wavelength range, is one of the major sources of tissue autofluorescence (AF) and AF imaging systems are now available. With their use, however, it is important to take into account tissue changes other than, or in addition to, changes in gross tissue morphology. These may include alterations in the local blood volume, tissue metabolic activity, and relative fluorophore concentrations. New AF imaging systems are very easy to use, because white light endoscopy can be changed to AF at the push of a button, and hold great promise for diagnosis of early carcinomas and premalignant lesions in the GI tract. In particular, AF endoscopy has potential for identification of small or flat tumors, tumor margins and premalignant lesions in Barrett’s esophagus, as well as for assessing tumor grade and response to therapy. However, large-scale studies are needed to clarify the clinical impact of this new diagnostic approach. The Japan Academy 2007-12 /pmc/articles/PMC3859293/ /pubmed/24367149 http://dx.doi.org/10.2183/pjab/83.248 Text en © 2007 The Japan Academy This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Tajiri, Hisao |
| spellingShingle |
Tajiri, Hisao Autofluorescence endoscopy for the gastrointestinal tract |
| author_facet |
Tajiri, Hisao |
| author_sort |
Tajiri, Hisao |
| title |
Autofluorescence endoscopy for the gastrointestinal tract |
| title_short |
Autofluorescence endoscopy for the gastrointestinal tract |
| title_full |
Autofluorescence endoscopy for the gastrointestinal tract |
| title_fullStr |
Autofluorescence endoscopy for the gastrointestinal tract |
| title_full_unstemmed |
Autofluorescence endoscopy for the gastrointestinal tract |
| title_sort |
autofluorescence endoscopy for the gastrointestinal tract |
| description |
This review focuses on our basic study results and clinical experience of fluorescence endoscopy for the gastrointestinal (GI) tract. Collagen, which fluoresces in the green wavelength range, is one of the major sources of tissue autofluorescence (AF) and AF imaging systems are now available. With their use, however, it is important to take into account tissue changes other than, or in addition to, changes in gross tissue morphology. These may include alterations in the local blood volume, tissue metabolic activity, and relative fluorophore concentrations. New AF imaging systems are very easy to use, because white light endoscopy can be changed to AF at the push of a button, and hold great promise for diagnosis of early carcinomas and premalignant lesions in the GI tract. In particular, AF endoscopy has potential for identification of small or flat tumors, tumor margins and premalignant lesions in Barrett’s esophagus, as well as for assessing tumor grade and response to therapy. However, large-scale studies are needed to clarify the clinical impact of this new diagnostic approach. |
| publisher |
The Japan Academy |
| publishDate |
2007 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859293/ |
| _version_ |
1612037408010797056 |