Natural Killer Cell-Dependent Anti-Fibrotic Pathway in Liver Injury via Toll-Like Receptor-9

Natural Killer Cell-Dependent Anti-Fibrotic Pathway in Liver Injury via Toll-Like Receptor-9

The toll-like receptor-9 (TLR9) agonist cytosine phosphate guanine (CpG), activates hepatic stellate cells (HSCs) and mediates fibrosis. We investigated the TLR9 effects on lymphocyte/HSCs interactions. Liver fibrosis was induced in wild-type (WT) mice by intra-peritoneal carbon-tetrachloride (CCl4)...

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Bibliographic Details
Main Authors: Abu-Tair, Lina, Axelrod, Jonathan H., Doron, Sarit, Ovadya, Yossi, Krizhanovsky, Valery, Galun, Eithan, Amer, Johnny, Safadi, Rifaat
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858328/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858328/

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