Discovery of a metabolic alternative to the classical mevalonate pathway
Eukarya, Archaea, and some Bacteria encode all or part of the essential mevalonate (MVA) metabolic pathway clinically modulated using statins. Curiously, two components of the MVA pathway are often absent from archaeal genomes. The search for these missing elements led to the discovery of isopenteny...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
eLife Sciences Publications, Ltd
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857490/ |