Moderate Hypoxia Followed by Reoxygenation Results in Blood-Brain Barrier Breakdown via Oxidative Stress-Dependent Tight-Junction Protein Disruption

Moderate Hypoxia Followed by Reoxygenation Results in Blood-Brain Barrier Breakdown via Oxidative Stress-Dependent Tight-Junction Protein Disruption

Re-canalization of cerebral vessels in ischemic stroke is pivotal to rescue dysfunctional brain areas that are exposed to moderate hypoxia within the penumbra from irreversible cell death. Goal of the present study was to evaluate the effect of moderate hypoxia followed by reoxygenation (MHR) on the...

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Bibliographic Details
Main Authors: Zehendner, Christoph M., Librizzi, Laura, Hedrich, Jana, Bauer, Nina M., Angamo, Eskedar A., de Curtis, Marco, Luhmann, Heiko J.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855783/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855783/

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