Telmisartan Ameliorates Fibrocystic Liver Disease in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease

Human autosomal recessive polycystic kidney disease (ARPKD) produces kidneys which are massively enlarged due to multiple cysts, hypertension, and congenital hepatic fibrosis characterized by dilated bile ducts and portal hypertension. The PCK rat is an orthologous model of human ARPKD with numerous...

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Bibliographic Details
Main Authors: Yoshihara, Daisuke, Kugita, Masanori, Sasaki, Mai, Horie, Shigeo, Nakanishi, Koichi, Abe, Takaaki, Aukema, Harold M., Yamaguchi, Tamio, Nagao, Shizuko
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855683/