EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex

Brown adipose tissue (BAT) dissipates chemical energy in the form of heat as a defense against hypothermia and obesity. Current evidence indicates that brown adipocytes arise from Myf5+ dermotomal precursors through the action of PRDM16 (PR domain containing protein16) transcriptional complex 1,2. H...

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Bibliographic Details
Main Authors: Ohno, Haruya, Shinoda, Kosaku, Ohyama, Kana, Sharp, Louis Z., Kajimura, Shingo
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855638/