Mycobacterial MazG Safeguards Genetic Stability via Housecleaning of 5-OH-dCTP

Generation of reactive oxygen species and reactive nitrogen species in phagocytes is an important innate immune response mechanism to eliminate microbial pathogens. It is known that deoxynucleotides (dNTPs), the precursor nucleotides to DNA synthesis, are one group of the significant targets for the...

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Bibliographic Details
Main Authors: Lyu, Liang-Dong, Tang, Bi-Kui, Fan, Xiao-Yong, Ma, Hui, Zhao, Guo-Ping
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855555/