Implication of HLA-DMA Alleles in Corsican IDDM

The HLA-DM molecule catalyses the CLIP/antigen peptide exchange in the classical class II peptide-binding groove. As such, DM is an antigen presentation regulator and may be linked to autoimmune diseases. Using PCR derived methods, a relationship was revealed between DM gene polymorphism and IDDM, i...

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Bibliographic Details
Main Authors: Cucchi-Mouillot, P., Lai, S., Carcassi, C., Sorba, P., Stuart-Simoni, M., Amoros, J.-P., Genetet, B., Haras, D., Contu, L.
Format: Online
Language:English
Published: IOS Press 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851055/