PRICKLE1 Interaction with SYNAPSIN I Reveals a Role in Autism Spectrum Disorders

PRICKLE1 Interaction with SYNAPSIN I Reveals a Role in Autism Spectrum Disorders

The frequent comorbidity of Autism Spectrum Disorders (ASDs) with epilepsy suggests a shared underlying genetic susceptibility; several genes, when mutated, can contribute to both disorders. Recently, PRICKLE1 missense mutations were found to segregate with ASD. However, the mechanism by which mutat...

Full description

Bibliographic Details
Main Authors: Paemka, Lily, Mahajan, Vinit B., Skeie, Jessica M., Sowers, Levi P., Ehaideb, Salleh N., Gonzalez-Alegre, Pedro, Sasaoka, Toshikuni, Tao, Hirotaka, Miyagi, Asuka, Ueno, Naoto, Takao, Keizo, Miyakawa, Tsuyoshi, Wu, Shu, Darbro, Benjamin W., Ferguson, Polly J., Pieper, Andrew A., Britt, Jeremiah K., Wemmie, John A., Rudd, Danielle S., Wassink, Thomas, El-Shanti, Hatem, Mefford, Heather C., Carvill, Gemma L., Manak, J. Robert, Bassuk, Alexander G.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849077/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849077/

Similar Items