Immunochemical Fecal Occult Blood Test for Detection of Advanced Colonic Adenomas and Colorectal Cancer: Comparison with Colonoscopy Results

Background. Fecal immunochemical tests (FITs) have been used for colorectal cancer (CRC) screening in several countries. There is lack of information concerning diagnostic performances of this method in Brazil. Methods. Patients scheduled for elective colonoscopy provided one stool sample one week...

Full description

Bibliographic Details
Main Authors:	Viana Freitas, Bianca Rosa, Kibune Nagasako, Cristiane, Pavan, Celia Regina, Silva Lorena, Sônia Letícia, Guerrazzi, Fabio, Saddy Rodrigues Coy, Cláudio, Ayrizono, Maria de Lourdes S., Mesquita, Maria Aparecida
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844264/

id	pubmed-3844264
recordtype	oai_dc
spelling	pubmed-38442642013-12-08 Immunochemical Fecal Occult Blood Test for Detection of Advanced Colonic Adenomas and Colorectal Cancer: Comparison with Colonoscopy Results Viana Freitas, Bianca Rosa Kibune Nagasako, Cristiane Pavan, Celia Regina Silva Lorena, Sônia Letícia Guerrazzi, Fabio Saddy Rodrigues Coy, Cláudio Ayrizono, Maria de Lourdes S. Mesquita, Maria Aparecida Research Article Background. Fecal immunochemical tests (FITs) have been used for colorectal cancer (CRC) screening in several countries. There is lack of information concerning diagnostic performances of this method in Brazil. Methods. Patients scheduled for elective colonoscopy provided one stool sample one week before colonoscopy. The accuracy of a qualitative FIT for detection of CRC and advanced adenomas was determined. Results. Overall 302 patients completed the study. Among them, 53.5% were high risk patients referred for screening or surveillance. Nine (3%) CRCs and 11 (3.6%) advanced adenomas were detected by colonoscopy. Sensitivity and specificity for CRC were, respectively, 88.9% and 87.6%. For advanced adenomas, sensitivity was 63.6% and specificity 87.6%. Conclusion. Our results showed good sensitivity and specificity of the FIT for detecting advanced neoplasias. This method may be a valuable tool for future screening programs in Brazil. Hindawi Publishing Corporation 2013 2013-11-11 /pmc/articles/PMC3844264/ /pubmed/24319453 http://dx.doi.org/10.1155/2013/384561 Text en Copyright © 2013 Bianca Rosa Viana Freitas et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Viana Freitas, Bianca Rosa Kibune Nagasako, Cristiane Pavan, Celia Regina Silva Lorena, Sônia Letícia Guerrazzi, Fabio Saddy Rodrigues Coy, Cláudio Ayrizono, Maria de Lourdes S. Mesquita, Maria Aparecida
spellingShingle	Viana Freitas, Bianca Rosa Kibune Nagasako, Cristiane Pavan, Celia Regina Silva Lorena, Sônia Letícia Guerrazzi, Fabio Saddy Rodrigues Coy, Cláudio Ayrizono, Maria de Lourdes S. Mesquita, Maria Aparecida Immunochemical Fecal Occult Blood Test for Detection of Advanced Colonic Adenomas and Colorectal Cancer: Comparison with Colonoscopy Results
author_facet	Viana Freitas, Bianca Rosa Kibune Nagasako, Cristiane Pavan, Celia Regina Silva Lorena, Sônia Letícia Guerrazzi, Fabio Saddy Rodrigues Coy, Cláudio Ayrizono, Maria de Lourdes S. Mesquita, Maria Aparecida
author_sort	Viana Freitas, Bianca Rosa
title	Immunochemical Fecal Occult Blood Test for Detection of Advanced Colonic Adenomas and Colorectal Cancer: Comparison with Colonoscopy Results
title_short	Immunochemical Fecal Occult Blood Test for Detection of Advanced Colonic Adenomas and Colorectal Cancer: Comparison with Colonoscopy Results
title_full	Immunochemical Fecal Occult Blood Test for Detection of Advanced Colonic Adenomas and Colorectal Cancer: Comparison with Colonoscopy Results
title_fullStr	Immunochemical Fecal Occult Blood Test for Detection of Advanced Colonic Adenomas and Colorectal Cancer: Comparison with Colonoscopy Results
title_full_unstemmed	Immunochemical Fecal Occult Blood Test for Detection of Advanced Colonic Adenomas and Colorectal Cancer: Comparison with Colonoscopy Results
title_sort	immunochemical fecal occult blood test for detection of advanced colonic adenomas and colorectal cancer: comparison with colonoscopy results
description	Background. Fecal immunochemical tests (FITs) have been used for colorectal cancer (CRC) screening in several countries. There is lack of information concerning diagnostic performances of this method in Brazil. Methods. Patients scheduled for elective colonoscopy provided one stool sample one week before colonoscopy. The accuracy of a qualitative FIT for detection of CRC and advanced adenomas was determined. Results. Overall 302 patients completed the study. Among them, 53.5% were high risk patients referred for screening or surveillance. Nine (3%) CRCs and 11 (3.6%) advanced adenomas were detected by colonoscopy. Sensitivity and specificity for CRC were, respectively, 88.9% and 87.6%. For advanced adenomas, sensitivity was 63.6% and specificity 87.6%. Conclusion. Our results showed good sensitivity and specificity of the FIT for detecting advanced neoplasias. This method may be a valuable tool for future screening programs in Brazil.
publisher	Hindawi Publishing Corporation
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844264/
_version_	1612031883772690432

Immunochemical Fecal Occult Blood Test for Detection of Advanced Colonic Adenomas and Colorectal Cancer: Comparison with Colonoscopy Results

Similar Items