The tethering complex HOPS catalyzes assembly of the soluble SNARE Vam7 into fusogenic trans-SNARE complexes
Large tethering complexes play an essential role in many intracellular membrane fusion events, yet their mode of action is poorly understood. A new function of the HOPS complex is uncovered in facilitating vacuolar fusion, the specific recruitment of the soluble SNARE Vam7 for the formation of fusog...
| Main Authors: | , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2013
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843000/ |