Long exposure to mature ooplasm can alter DNA methylation at imprinted loci in non-growing oocytes but not in prospermatogonia
DNA methylation imprints that are established in spermatogenesis and oogenesis are essential for functional gametes. However, the mechanisms underlying gamete-specific imprinting remain unclear. In this study, we investigated whether male and female gametes derived from newborn mice are epigenetical...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Bioscientifica Ltd
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842912/ |