Survey of Innate Immune Responses to Burkholderia pseudomallei in Human Blood Identifies a Central Role for Lipopolysaccharide

B. pseudomallei is a gram-negative bacterium that causes the tropical infection melioidosis. In northeast Thailand, mortality from melioidosis approaches 40%. As exemplified by the lipopolysaccharide-Toll-like receptor 4 interaction, innate immune responses to invading bacteria are precipitated by...

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Bibliographic Details
Main Authors: Chantratita, Narisara, Tandhavanant, Sarunporn, Myers, Nicolle D., Seal, Sudeshna, Arayawichanont, Arkhom, Kliangsa-ad, Aroonsri, Hittle, Lauren E., Ernst, Robert K., Emond, Mary J., Wurfel, Mark M., Day, Nicholas P. J., Peacock, Sharon J., West, T. Eoin
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841221/