Analyses of the effects of Gq protein on the activated states of the muscarinic M3 receptor and the purinergic P2Y1 receptor
G protein–coupled receptors (GPCRs) cause various cellular responses through activating heterotrimeric G protein upon the agonist binding. The interaction with G protein has been suggested to stabilize the agonist-bound active conformation of GPCRs. We previously reported the effects of Gq protein o...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Blackwell Publishing Ltd
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841061/ |