MSI-Testing in Hereditary Non-Polyposis Colorectal Carcinoma (HNPCC)

Genomic instability at simple repeated sequences, termed microsatellite instability (MSI), plays an important role in the analysis of sporadic and hereditary colon cancers. In hereditary non-polyposis colorectal cancer syndrome (HNPCC) more than 90% of cases show MSI, whereas only 10–15% of sporadic...

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Bibliographic Details
Main Authors: Müller, Annegret, Edmonston, Tina Bocker, Dietmaier, Wolfgang, Büttner, Reinhard, Fishel, Richard, Rüschoff, Josef
Format: Online
Language:English
Published: IOS Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839272/