Herpes Simplex Virus 1 Counteracts Tetherin Restriction via Its Virion Host Shutoff Activity
The interferon-inducible membrane protein tetherin (Bst-2, or CD317) is an antiviral factor that inhibits enveloped virus release by cross-linking newly formed virus particles to the producing cell. The majority of viruses that are sensitive to tetherin restriction appear to be those that acquire th...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
American Society for Microbiology
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838292/ |