Herpes Simplex Virus 1 Counteracts Tetherin Restriction via Its Virion Host Shutoff Activity

The interferon-inducible membrane protein tetherin (Bst-2, or CD317) is an antiviral factor that inhibits enveloped virus release by cross-linking newly formed virus particles to the producing cell. The majority of viruses that are sensitive to tetherin restriction appear to be those that acquire th...

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Bibliographic Details
Main Authors: Zenner, Helen L., Mauricio, Rui, Banting, George, Crump, Colin M.
Format: Online
Language:English
Published: American Society for Microbiology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838292/