FXR an emerging therapeutic target for the treatment of atherosclerosis

Atherosclerosis is the leading cause of illness and death. Therapeutic strategies aimed at reducing cholesterol plasma levels have shown efficacy in either reducing progression of atherosclerotic plaques and atherosclerosis-related mortality. The farnesoid-X-receptor (FXR) is a member of metabolic n...

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Bibliographic Details
Main Authors: Mencarelli, Andrea, Fiorucci, Stefano
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837604/