Increased Persistent Sodium Current Due to Decreased PI3K Signaling Contributes to QT Prolongation in the Diabetic Heart

Diabetes is an independent risk factor for sudden cardiac death and ventricular arrhythmia complications of acute coronary syndrome. Prolongation of the QT interval on the electrocardiogram is also a risk factor for arrhythmias and sudden death, and the increased prevalence of QT prolongation is an...

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Bibliographic Details
Main Authors: Lu, Zhongju, Jiang, Ya-Ping, Wu, Chia-Yen C., Ballou, Lisa M., Liu, Shengnan, Carpenter, Eileen S., Rosen, Michael R., Cohen, Ira S., Lin, Richard Z.
Format: Online
Language:English
Published: American Diabetes Association 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837031/