Defining the Range of Pathogens Susceptible to Ifitm3 Restriction Using a Knockout Mouse Model

Defining the Range of Pathogens Susceptible to Ifitm3 Restriction Using a Knockout Mouse Model

The interferon-inducible transmembrane (IFITM) family of proteins has been shown to restrict a broad range of viruses in vitro and in vivo by halting progress through the late endosomal pathway. Further, single nucleotide polymorphisms (SNPs) in its sequence have been linked with risk of developing...

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Bibliographic Details
Main Authors: Everitt, Aaron R., Clare, Simon, McDonald, Jacqueline U., Kane, Leanne, Harcourt, Katherine, Ahras, Malika, Lall, Amar, Hale, Christine, Rodgers, Angela, Young, Douglas B., Haque, Ashraful, Billker, Oliver, Tregoning, John S., Dougan, Gordon, Kellam, Paul
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836756/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836756/

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