Commensal Bacteria-Dependent Indole Production Enhances Epithelial Barrier Function in the Colon

Microbiota have been shown to have a great influence on functions of intestinal epithelial cells (ECs). The role of indole as a quorum-sensing (QS) molecule mediating intercellular signals in bacteria has been well appreciated. However, it remains unknown whether indole has beneficial effects on mai...

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Bibliographic Details
Main Authors: Shimada, Yosuke, Kinoshita, Makoto, Harada, Kazuo, Mizutani, Masafumi, Masahata, Kazunori, Kayama, Hisako, Takeda, Kiyoshi
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835565/