Markers for Detection of Prostate Cancer

Early detection of prostate cancer is problematic, not just because of uncertainly whether a diagnosis will benefit an individual patient, but also as a result of the imprecise and invasive nature of establishing a diagnosis by biopsy. Despite its low sensitivity and specificity for identifying pati...

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Main Authors:	Clarke, Raymond A., Schirra, Horst J., Catto, James W., Lavin, Martin F., Gardiner, Robert A.
Format:	Online
Language:	English
Published:	MDPI 2010
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835122/

id	pubmed-3835122
recordtype	oai_dc
spelling	pubmed-38351222013-11-21 Markers for Detection of Prostate Cancer Clarke, Raymond A. Schirra, Horst J. Catto, James W. Lavin, Martin F. Gardiner, Robert A. Review Early detection of prostate cancer is problematic, not just because of uncertainly whether a diagnosis will benefit an individual patient, but also as a result of the imprecise and invasive nature of establishing a diagnosis by biopsy. Despite its low sensitivity and specificity for identifying patients harbouring prostate cancer, serum prostate specific antigen (PSA) has become established as the most reliable and widely-used diagnostic marker for this condition. In its wake, many other markers have been described and evaluated. This review focuses on the supporting evidence for the most prominent of these for detection and also for predicting outcome in prostate cancer. MDPI 2010-06-04 /pmc/articles/PMC3835122/ /pubmed/24281110 http://dx.doi.org/10.3390/cancers2021125 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Clarke, Raymond A. Schirra, Horst J. Catto, James W. Lavin, Martin F. Gardiner, Robert A.
spellingShingle	Clarke, Raymond A. Schirra, Horst J. Catto, James W. Lavin, Martin F. Gardiner, Robert A. Markers for Detection of Prostate Cancer
author_facet	Clarke, Raymond A. Schirra, Horst J. Catto, James W. Lavin, Martin F. Gardiner, Robert A.
author_sort	Clarke, Raymond A.
title	Markers for Detection of Prostate Cancer
title_short	Markers for Detection of Prostate Cancer
title_full	Markers for Detection of Prostate Cancer
title_fullStr	Markers for Detection of Prostate Cancer
title_full_unstemmed	Markers for Detection of Prostate Cancer
title_sort	markers for detection of prostate cancer
description	Early detection of prostate cancer is problematic, not just because of uncertainly whether a diagnosis will benefit an individual patient, but also as a result of the imprecise and invasive nature of establishing a diagnosis by biopsy. Despite its low sensitivity and specificity for identifying patients harbouring prostate cancer, serum prostate specific antigen (PSA) has become established as the most reliable and widely-used diagnostic marker for this condition. In its wake, many other markers have been described and evaluated. This review focuses on the supporting evidence for the most prominent of these for detection and also for predicting outcome in prostate cancer.
publisher	MDPI
publishDate	2010
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835122/
_version_	1612029135009349632

Markers for Detection of Prostate Cancer

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