Evaluation of Embryotoxic Potential of Olaquindox and Vitamin A in Micromass Culture and in Rats

Limb bud (LB) and central nerve system (CNS) cells were prepared from 12.5 day old pregnant female Crj:CD (SD) rats and treated with olaquindox and vitamin A. Cytotoxicity and inhibition on differentiation were measured in each cell. Three doses of olaquindox (4, 21 and 100 mgkg) , and 0.2 and 75 mg...

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Bibliographic Details
Main Authors: Kang, Hwan Goo, Ku, Hyun Ok, Jeong, Sang Hee, Cho, Joon Hyoung, Son, Seong Wan
Format: Online
Language:English
Published: The Korean Society of Toxicology 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834482/