Targeting of Histone Deacetylases to Reactivate Tumour Suppressor Genes and Its Therapeutic Potential in a Human Cervical Cancer Xenograft Model

Targeting of Histone Deacetylases to Reactivate Tumour Suppressor Genes and Its Therapeutic Potential in a Human Cervical Cancer Xenograft Model

Aberrant histone acetylation plays an essential role in the neoplastic process via the epigenetic silencing of tumour suppressor genes (TSGs); therefore, the inhibition of histone deacetylases (HDAC) has become a promising target in cancer therapeutics. To investigate the correlation of histone acet...

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Bibliographic Details
Main Authors: Feng, Dingqing, Wu, Jiao, Tian, Yuan, Zhou, Hu, Zhou, Ying, Hu, Weiping, Zhao, Weidong, Wei, Haiming, Ling, Bin, Ma, Chunhong
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834007/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834007/

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