Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México

Several polymorphisms related to hypertension, thrombophilia, and oxidative stress has been associated with the development of cardiovascular disease. We analyzed the frequency of M235T angiotensinogen (AGT), A222V 5,10 methylenete-trahydrofolate reductase (MTHFR), L33P glycoprotein IIIa (GPIIIa), a...

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Main Authors: Juárez-Velázquez, Rocio, Canto, Patricia, Canto-Cetina, Thelma, Rangel-Villalobos, Hector, Rosas-Vargas, Haydee, Rodríguez, Maricela, Canizales-Quinteros, Samuel, Velázquez Wong, Ana Claudia, Ordoñez-Razo, Rosa María, Vilchis-Dorantes, Guadalupe, Coral-Vázquez, Ramón Mauricio
Format: Online
Language:English
Published: IOS Press 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833604/
id pubmed-3833604
recordtype oai_dc
spelling pubmed-38336042013-12-17 Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México Juárez-Velázquez, Rocio Canto, Patricia Canto-Cetina, Thelma Rangel-Villalobos, Hector Rosas-Vargas, Haydee Rodríguez, Maricela Canizales-Quinteros, Samuel Velázquez Wong, Ana Claudia Ordoñez-Razo, Rosa María Vilchis-Dorantes, Guadalupe Coral-Vázquez, Ramón Mauricio Other Several polymorphisms related to hypertension, thrombophilia, and oxidative stress has been associated with the development of cardiovascular disease. We analyzed the frequency of M235T angiotensinogen (AGT), A222V 5,10 methylenete-trahydrofolate reductase (MTHFR), L33P glycoprotein IIIa (GPIIIa), and I105V glutathione S-transferase P1 (GSTP1) polymorphisms in 285 individuals belonging to Mexican-Mestizo and five Amerindian population from México, by real time PCR allelic discrimination. Allele and genotype frequencies were compared using χ2 tests. IOS Press 2010 2010-06-29 /pmc/articles/PMC3833604/ /pubmed/20592457 http://dx.doi.org/10.3233/DMA-2010-0712 Text en Copyright © 2010 Hindawi Publishing Corporation.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Juárez-Velázquez, Rocio
Canto, Patricia
Canto-Cetina, Thelma
Rangel-Villalobos, Hector
Rosas-Vargas, Haydee
Rodríguez, Maricela
Canizales-Quinteros, Samuel
Velázquez Wong, Ana Claudia
Ordoñez-Razo, Rosa María
Vilchis-Dorantes, Guadalupe
Coral-Vázquez, Ramón Mauricio
spellingShingle Juárez-Velázquez, Rocio
Canto, Patricia
Canto-Cetina, Thelma
Rangel-Villalobos, Hector
Rosas-Vargas, Haydee
Rodríguez, Maricela
Canizales-Quinteros, Samuel
Velázquez Wong, Ana Claudia
Ordoñez-Razo, Rosa María
Vilchis-Dorantes, Guadalupe
Coral-Vázquez, Ramón Mauricio
Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México
author_facet Juárez-Velázquez, Rocio
Canto, Patricia
Canto-Cetina, Thelma
Rangel-Villalobos, Hector
Rosas-Vargas, Haydee
Rodríguez, Maricela
Canizales-Quinteros, Samuel
Velázquez Wong, Ana Claudia
Ordoñez-Razo, Rosa María
Vilchis-Dorantes, Guadalupe
Coral-Vázquez, Ramón Mauricio
author_sort Juárez-Velázquez, Rocio
title Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México
title_short Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México
title_full Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México
title_fullStr Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México
title_full_unstemmed Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México
title_sort analysis of polymorphisms in genes (agt, mthfr, gpiiia, and gstp1) associated with hypertension, thrombophilia and oxidative stress in mestizo and amerindian populations of méxico
description Several polymorphisms related to hypertension, thrombophilia, and oxidative stress has been associated with the development of cardiovascular disease. We analyzed the frequency of M235T angiotensinogen (AGT), A222V 5,10 methylenete-trahydrofolate reductase (MTHFR), L33P glycoprotein IIIa (GPIIIa), and I105V glutathione S-transferase P1 (GSTP1) polymorphisms in 285 individuals belonging to Mexican-Mestizo and five Amerindian population from México, by real time PCR allelic discrimination. Allele and genotype frequencies were compared using χ2 tests.
publisher IOS Press
publishDate 2010
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833604/
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