Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México
Several polymorphisms related to hypertension, thrombophilia, and oxidative stress has been associated with the development of cardiovascular disease. We analyzed the frequency of M235T angiotensinogen (AGT), A222V 5,10 methylenete-trahydrofolate reductase (MTHFR), L33P glycoprotein IIIa (GPIIIa), a...
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2010
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833604/ |
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pubmed-38336042013-12-17 Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México Juárez-Velázquez, Rocio Canto, Patricia Canto-Cetina, Thelma Rangel-Villalobos, Hector Rosas-Vargas, Haydee Rodríguez, Maricela Canizales-Quinteros, Samuel Velázquez Wong, Ana Claudia Ordoñez-Razo, Rosa María Vilchis-Dorantes, Guadalupe Coral-Vázquez, Ramón Mauricio Other Several polymorphisms related to hypertension, thrombophilia, and oxidative stress has been associated with the development of cardiovascular disease. We analyzed the frequency of M235T angiotensinogen (AGT), A222V 5,10 methylenete-trahydrofolate reductase (MTHFR), L33P glycoprotein IIIa (GPIIIa), and I105V glutathione S-transferase P1 (GSTP1) polymorphisms in 285 individuals belonging to Mexican-Mestizo and five Amerindian population from México, by real time PCR allelic discrimination. Allele and genotype frequencies were compared using χ2 tests. IOS Press 2010 2010-06-29 /pmc/articles/PMC3833604/ /pubmed/20592457 http://dx.doi.org/10.3233/DMA-2010-0712 Text en Copyright © 2010 Hindawi Publishing Corporation. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Juárez-Velázquez, Rocio Canto, Patricia Canto-Cetina, Thelma Rangel-Villalobos, Hector Rosas-Vargas, Haydee Rodríguez, Maricela Canizales-Quinteros, Samuel Velázquez Wong, Ana Claudia Ordoñez-Razo, Rosa María Vilchis-Dorantes, Guadalupe Coral-Vázquez, Ramón Mauricio |
spellingShingle |
Juárez-Velázquez, Rocio Canto, Patricia Canto-Cetina, Thelma Rangel-Villalobos, Hector Rosas-Vargas, Haydee Rodríguez, Maricela Canizales-Quinteros, Samuel Velázquez Wong, Ana Claudia Ordoñez-Razo, Rosa María Vilchis-Dorantes, Guadalupe Coral-Vázquez, Ramón Mauricio Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México |
author_facet |
Juárez-Velázquez, Rocio Canto, Patricia Canto-Cetina, Thelma Rangel-Villalobos, Hector Rosas-Vargas, Haydee Rodríguez, Maricela Canizales-Quinteros, Samuel Velázquez Wong, Ana Claudia Ordoñez-Razo, Rosa María Vilchis-Dorantes, Guadalupe Coral-Vázquez, Ramón Mauricio |
author_sort |
Juárez-Velázquez, Rocio |
title |
Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México |
title_short |
Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México |
title_full |
Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México |
title_fullStr |
Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México |
title_full_unstemmed |
Analysis of Polymorphisms in Genes (AGT, MTHFR, GPIIIa, and GSTP1) Associated with Hypertension, Thrombophilia and Oxidative Stress in Mestizo and Amerindian Populations of México |
title_sort |
analysis of polymorphisms in genes (agt, mthfr, gpiiia, and gstp1) associated with hypertension, thrombophilia and oxidative stress in mestizo and amerindian populations of méxico |
description |
Several polymorphisms related to hypertension, thrombophilia, and oxidative stress has been associated with the development of cardiovascular disease. We analyzed the frequency of M235T angiotensinogen (AGT), A222V 5,10 methylenete-trahydrofolate reductase (MTHFR), L33P glycoprotein IIIa (GPIIIa), and I105V glutathione S-transferase P1 (GSTP1) polymorphisms in 285 individuals belonging to Mexican-Mestizo and five Amerindian population from México, by real time PCR allelic discrimination. Allele and genotype frequencies were compared using χ2 tests. |
publisher |
IOS Press |
publishDate |
2010 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833604/ |
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1612028545453785088 |