Lipid Measures and Cardiovascular Disease Prediction

Traditional lipid measures are the cornerstone of risk assessment and treatment goals in cardiovascular prevention. Whereas the association between total, LDL-, HDL-cholesterol and cardiovascular disease risk has been generally acknowledged, the rather poor capacity to distinguish between patients w...

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Main Authors: van Wijk, Diederik F., Stroes, Erik S. G., Kastelein, John J. P.
Format: Online
Language:English
Published: IOS Press 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833241/
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recordtype oai_dc
spelling pubmed-38332412013-12-10 Lipid Measures and Cardiovascular Disease Prediction van Wijk, Diederik F. Stroes, Erik S. G. Kastelein, John J. P. Other Traditional lipid measures are the cornerstone of risk assessment and treatment goals in cardiovascular prevention. Whereas the association between total, LDL-, HDL-cholesterol and cardiovascular disease risk has been generally acknowledged, the rather poor capacity to distinguish between patients who will and those who will not develop cardiovascular disease has prompted the search for further refinement of these traditional measures. A thorough understanding of lipid metabolism is mandatory to understand recent developments in this area. After a brief overview of lipid metabolism we will discuss the epidemiological data of total, LDL- and HDL-cholesterol and focus on recent advances in measurements of these lipoproteins. In addition we will discuss the role of triglycerides and the apolipoprotein B–A-I ratio on the incidence of cardiovascular disease. IOS Press 2009 2009-09-21 /pmc/articles/PMC3833241/ /pubmed/19773610 http://dx.doi.org/10.3233/DMA-2009-0636 Text en Copyright © 2009 Hindawi Publishing Corporation.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author van Wijk, Diederik F.
Stroes, Erik S. G.
Kastelein, John J. P.
spellingShingle van Wijk, Diederik F.
Stroes, Erik S. G.
Kastelein, John J. P.
Lipid Measures and Cardiovascular Disease Prediction
author_facet van Wijk, Diederik F.
Stroes, Erik S. G.
Kastelein, John J. P.
author_sort van Wijk, Diederik F.
title Lipid Measures and Cardiovascular Disease Prediction
title_short Lipid Measures and Cardiovascular Disease Prediction
title_full Lipid Measures and Cardiovascular Disease Prediction
title_fullStr Lipid Measures and Cardiovascular Disease Prediction
title_full_unstemmed Lipid Measures and Cardiovascular Disease Prediction
title_sort lipid measures and cardiovascular disease prediction
description Traditional lipid measures are the cornerstone of risk assessment and treatment goals in cardiovascular prevention. Whereas the association between total, LDL-, HDL-cholesterol and cardiovascular disease risk has been generally acknowledged, the rather poor capacity to distinguish between patients who will and those who will not develop cardiovascular disease has prompted the search for further refinement of these traditional measures. A thorough understanding of lipid metabolism is mandatory to understand recent developments in this area. After a brief overview of lipid metabolism we will discuss the epidemiological data of total, LDL- and HDL-cholesterol and focus on recent advances in measurements of these lipoproteins. In addition we will discuss the role of triglycerides and the apolipoprotein B–A-I ratio on the incidence of cardiovascular disease.
publisher IOS Press
publishDate 2009
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833241/
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