Intranuclear Crosstalk between Extracellular Regulated Kinase1/2 and Signal Transducer and Activator of Transcription 3 Regulates JEG-3 Choriocarcinoma Cell Invasion and Proliferation

Intranuclear Crosstalk between Extracellular Regulated Kinase1/2 and Signal Transducer and Activator of Transcription 3 Regulates JEG-3 Choriocarcinoma Cell Invasion and Proliferation

Invasiveness of trophoblast and choriocarcinoma cells is in part mediated via leukemia inhibitory factor- (LIF-) induced activation of signal transducer and activator of transcription 3 (STAT3). The regulation of STAT3 phosphorylation at its ser727 binding site, possible crosstalk with intracellular...

Full description

Bibliographic Details
Main Authors: Morales-Prieto, Diana M., Ospina-Prieto, Stephanie, Chaiwangyen, Wittaya, Weber, Maja, Hölters, Sebastian, Schleussner, Ekkehard, Fitzgerald, Justine S., Markert, Udo R.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833059/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833059/

Similar Items