Surgical Treatment of Pediatric Epileptic Encephalopathies
Pediatric epileptiform encephalopathies are a group of neurologically devastating disorders related to uncontrolled ictal and interictal epileptic activity, with a poor prognosis. Despite the number of pharmacological options for treatment of epilepsy, many of these patients are drug resistant. For...
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| Format: | Online |
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Hindawi Publishing Corporation
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833057/ |
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pubmed-38330572013-11-28 Surgical Treatment of Pediatric Epileptic Encephalopathies Fridley, J. Reddy, G. Curry, D. Agadi, S. Review Article Pediatric epileptiform encephalopathies are a group of neurologically devastating disorders related to uncontrolled ictal and interictal epileptic activity, with a poor prognosis. Despite the number of pharmacological options for treatment of epilepsy, many of these patients are drug resistant. For these patients with uncontrolled epilepsy, motor and/or neuropsychological deterioration is common. To prevent these secondary consequences, surgery is often considered as either a curative or a palliative option. Magnetic resonance imaging to look for epileptic lesions that may be surgically treated is an essential part of the workup for these patients. Many surgical procedures for the treatment of epileptiform encephalopathies have been reported in the literature. In this paper the evidence for these procedures for the treatment of pediatric epileptiform encephalopathies is reviewed. Hindawi Publishing Corporation 2013 2013-10-30 /pmc/articles/PMC3833057/ /pubmed/24288601 http://dx.doi.org/10.1155/2013/720841 Text en Copyright © 2013 J. Fridley et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Fridley, J. Reddy, G. Curry, D. Agadi, S. |
| spellingShingle |
Fridley, J. Reddy, G. Curry, D. Agadi, S. Surgical Treatment of Pediatric Epileptic Encephalopathies |
| author_facet |
Fridley, J. Reddy, G. Curry, D. Agadi, S. |
| author_sort |
Fridley, J. |
| title |
Surgical Treatment of Pediatric Epileptic Encephalopathies |
| title_short |
Surgical Treatment of Pediatric Epileptic Encephalopathies |
| title_full |
Surgical Treatment of Pediatric Epileptic Encephalopathies |
| title_fullStr |
Surgical Treatment of Pediatric Epileptic Encephalopathies |
| title_full_unstemmed |
Surgical Treatment of Pediatric Epileptic Encephalopathies |
| title_sort |
surgical treatment of pediatric epileptic encephalopathies |
| description |
Pediatric epileptiform encephalopathies are a group of neurologically devastating disorders related to uncontrolled ictal and interictal epileptic activity, with a poor prognosis. Despite the number of pharmacological options for treatment of epilepsy, many of these patients are drug resistant. For these patients with uncontrolled epilepsy, motor and/or neuropsychological deterioration is common. To prevent these secondary consequences, surgery is often considered as either a curative or a palliative option. Magnetic resonance imaging to look for epileptic lesions that may be surgically treated is an essential part of the workup for these patients. Many surgical procedures for the treatment of epileptiform encephalopathies have been reported in the literature. In this paper the evidence for these procedures for the treatment of pediatric epileptiform encephalopathies is reviewed. |
| publisher |
Hindawi Publishing Corporation |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833057/ |
| _version_ |
1612028312614338560 |