The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response

The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response

Direct class switching to IgE generates IgE+ GC cells that are highly apoptotic and do not contribute to the memory compartment, while sequential switching through an IgG+ intermediate results in the generation of long-lived IgE+ plasma cells.

Bibliographic Details
Main Authors: He, Jin-Shu, Meyer-Hermann, Michael, Xiangying, Deng, Zuan, Lim Yok, Jones, Leigh Ann, Ramakrishna, Lakshmi, de Vries, Victor C., Dolpady, Jayashree, Aina, Hoi, Joseph, Sabrina, Narayanan, Sriram, Subramaniam, Sharrada, Puthia, Manoj, Wong, Glenn, Xiong, Huizhong, Poidinger, Michael, Urban, Joseph F., Lafaille, Juan J., Curotto de Lafaille, Maria A.
Format: Online
Language:English
Published: The Rockefeller University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832920/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832920/

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